Documents/Downloads

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Fluoroquinolone Document Library

The following files are available for download or reading as a help to the fluoroquinolone victim community .

Disclaimer: This site may contain copyrighted material, the use of which has not always been specifically authorized by the copyright owner(s). Such material is made available for educational purposes, under the ‘fair use’ provision as provided for in Title 17 U.S.C. section 107 of the US Copyright Law.

[/fusion_text][fusion_content_boxes layout=”icon-with-title” columns=”3″ link_type=”” button_span=”” link_area=”” link_target=”” icon_align=”left” animation_type=”” animation_direction=”left” animation_speed=”0.3″ animation_delay=”” animation_offset=”” hide_on_mobile=”small-visibility,medium-visibility,large-visibility” class=”” id=”” title_size=”” heading_size=”2″ title_color=”” hue=”” saturation=”” lightness=”” alpha=”” body_color=”#000000″ backgroundcolor=”” icon=”” iconflip=”” iconrotate=”” iconspin=”no” iconcolor=”” icon_circle=”no” icon_circle_radius=”” circlecolor=”” circlebordersize=”” circlebordercolor=”” outercirclebordersize=”” outercirclebordercolor=”” icon_size=”35″ icon_hover_type=”none” hover_accent_color=”#3431f7″ image=”” image_id=”” image_max_width=”” margin_top=”” margin_bottom=””][fusion_content_box title=”Mitochondrial Retrograde Signaling in Fluoroquinolone Associated Disability, A Disease Theory” backgroundcolor=”” hue=”” saturation=”” lightness=”” alpha=”” icon=”fa-file-pdf fas” iconflip=”” iconrotate=”” iconspin=”” iconcolor=”#ff0000″ circlecolor=”” circlebordersize=”” circlebordercolor=”” outercirclebordersize=”” outercirclebordercolor=”” image=”” image_id=”” image_max_width=”” link=”https://www.dev.myquinstory.info/wp-content/uploads/2023/04/Mito-Retrograde-Theory-in-FQAD-2023-1.pdf” linktext=”Read More” link_target=”” animation_type=”” animation_direction=”left” animation_speed=”0.3″ animation_offset=””]

Publication: Research Hypothesis

Based on the large amount of anecdotal data collected over several years, combined with recent clinical diagnostics from a few cases of FQAD, this paper suggests a novel hypothesis.

[/fusion_content_box][fusion_content_box title=”Quick Guide to Fluoroquinolone Toxicity” backgroundcolor=”” hue=”” saturation=”” lightness=”” alpha=”” icon=”fa-file-pdf fas” iconflip=”” iconrotate=”” iconspin=”” iconcolor=”#ff0000″ circlecolor=”” circlebordersize=”” circlebordercolor=”” outercirclebordersize=”” outercirclebordercolor=”” image=”” image_id=”” image_max_width=”” link=”https://www.dev.myquinstory.info/wp-content/uploads/2024/01/Quick-Guide-to-FQ-Toxicity.pdf” linktext=”Read More” link_target=”” animation_type=”” animation_direction=”left” animation_speed=”0.3″ animation_offset=””]

Publication: Hand Out

This is a Fact Sheet or Quick Guide to Fluoroquinolone Antibiotic Toxicity.  It can be freely distributed and printed out as a quick reference and advocacy tool.

[/fusion_content_box][fusion_content_box title=”Fluoroquinolone-associated Suicide EJM 07/20/2018″ backgroundcolor=”” icon=”fa-file-pdf fas” iconflip=”” iconrotate=”” iconspin=”” iconcolor=”#ff0000″ circlecolor=”” circlebordersize=”” circlebordercolor=”” outercirclebordersize=”” outercirclebordercolor=”” image=”” image_id=”” image_max_width=”” link=”https://www.dev.myquinstory.info/wp-content/uploads/2018/07/Dr-Bennett-FQ-associated-suicide-EJIM.pdf” linktext=”Read More” link_target=”” animation_type=”” animation_direction=”left” animation_speed=”0.3″ animation_offset=””]

Academic Paper

Dr. Charles Bennett Suicide Paper for the European Journal of Medicine July 20 2018 produced with help from the FQ community.

[/fusion_content_box][fusion_content_box title=”FDA Anti-Infective Drugs Advisory Committee Transcript 11/05/2015″ backgroundcolor=”” icon=”fa-file-pdf fas” iconflip=”” iconrotate=”” iconspin=”” iconcolor=”#ff0000″ circlecolor=”” circlebordersize=”” circlebordercolor=”” outercirclebordersize=”” outercirclebordercolor=”” image=”” image_id=”” image_max_width=”” link=”https://www.dev.myquinstory.info/wp-content/uploads/2018/06/FDA-Anti-Infective-Drugs-Advisory-Committee-UCM477657-Transcript-110515.pdf” linktext=”Read More” link_target=”” animation_type=”” animation_direction=”left” animation_speed=”0.3″ animation_offset=””]

FDA Document

FDA JOINT MEETING OF THE ANTIMICROBIAL DRUGS ADVISORY COMMITTEE AND THE DRUG SAFETY AND RISK MANAGEMENT ADVISORY COMMITTEE  Transcript 11/05/2015

[/fusion_content_box][fusion_content_box title=”FDA Warnings of Permanent Peripheral Neuropathy 08/15/2013″ backgroundcolor=”” icon=”fa-file-pdf fas” iconflip=”” iconrotate=”” iconspin=”” iconcolor=”#ff0000″ circlecolor=”” circlebordersize=”” circlebordercolor=”” outercirclebordersize=”” outercirclebordercolor=”” image=”” image_id=”” image_max_width=”” link=”https://www.dev.myquinstory.info/wp-content/uploads/2018/06/FDA-UCM365078-081503-Warnings-of-Permanent-Peripheral-Neuropathy.pdf” linktext=”Read More” link_target=”” animation_type=”” animation_direction=”left” animation_speed=”0.3″ animation_offset=””]

FDA Document

FDA requires label changes to warn of risk for possibly permanent nerve damage from antibacterial fluoroquinolone drugs taken by mouth or by injection issued 08/15/2013

[/fusion_content_box][fusion_content_box title=”FDA Briefing Document Coining FQAD 11/05/2015″ backgroundcolor=”” icon=”fa-file-pdf fas” iconflip=”” iconrotate=”” iconspin=”” iconcolor=”#ff0202″ circlecolor=”” circlebordersize=”” circlebordercolor=”” outercirclebordersize=”” outercirclebordercolor=”” image=”” image_id=”” image_max_width=”” link=”https://www.dev.myquinstory.info/wp-content/uploads/2018/06/FDA-Briefing-Information-Nov-5-2015-Meeting-of-the-Antimicrobial-Drugs-Advisory-Committee-and-the-Drug-Safety-and-Risk-Management-Advisory-Committee-FQAD.pdf” linktext=”Read More” link_target=”” animation_type=”” animation_direction=”left” animation_speed=”0.3″ animation_offset=””]

FDA Document

FDA Briefing Document Joint Meeting of the Antimicrobial Drugs Advisory Committee and the Drug Safety and Risk Management Advisory Committee November 5, 2015 where the FDA coined “FQAD”

[/fusion_content_box][fusion_content_box title=”Activity of Quinolones against Mammalian Topoisomerase II 10/1993″ backgroundcolor=”” icon=”fa-file-pdf fas” iconflip=”” iconrotate=”” iconspin=”” iconcolor=”#ff0000″ circlecolor=”” circlebordersize=”” circlebordercolor=”” outercirclebordersize=”” outercirclebordercolor=”” image=”” image_id=”” image_max_width=”” link=”https://www.dev.myquinstory.info/wp-content/uploads/2013/09/Activity-of-Quinolones-Mammalian-Cells.pdf” linktext=”Read More” link_target=”” animation_type=”” animation_direction=”left” animation_speed=”0.3″ animation_offset=””]

Academic Paper

Drug Features That Contribute to the Activity of Quinolones against Mammalian Topoisomerase II and Cultured Cells: Correlation between Enhancement of Enzyme-Mediated DNA Cleavage In Vitro and Cytotoxic Potential October 1993

[/fusion_content_box][fusion_content_box title=”Adverse Reactions to Fluoroquinolones by James R. Roberts, MD 10/2008″ backgroundcolor=”” icon=”fa-file-pdf fas” iconflip=”” iconrotate=”” iconspin=”” iconcolor=”#ff0000″ circlecolor=”” circlebordersize=”” circlebordercolor=”” outercirclebordersize=”” outercirclebordercolor=”” image=”” image_id=”” image_max_width=”” link=”https://www.dev.myquinstory.info/wp-content/uploads/2012/03/james-roberts-MD-part1.pdf” linktext=”Read More ” link_target=”” animation_type=”” animation_direction=”left” animation_speed=”0.3″ animation_offset=””]

Article 

Adverse Reactions to Fluoroquinolones, written by James Roberts M.D. 2008 Emergency Medicine Newsletter

[/fusion_content_box][fusion_content_box title=”Nalidixic Acid Damage to mtDNA 1983″ backgroundcolor=”” icon=”fa-file-pdf fas” iconflip=”” iconrotate=”” iconspin=”” iconcolor=”#ff0000″ circlecolor=”” circlebordersize=”” circlebordercolor=”” outercirclebordersize=”” outercirclebordercolor=”” image=”” image_id=”” image_max_width=”” link=”https://www.dev.myquinstory.info/wp-content/uploads/2010/01/Castora-DNA-Synthesis-In-mam-mtDNA-1983.pdf” linktext=”Read More” link_target=”” animation_type=”” animation_direction=”left” animation_speed=”0.3″ animation_offset=””]

Academic Paper

The Effect of Bacerial DNA Gyrase Inhibitors on DNA Synthesis In Mammalian Mitochondria.  This paper documents that Naladixic Acid (grandfather of today’s FQ’s) damages mitochondrial DNA. 1983

[/fusion_content_box][fusion_content_box title=”Citizen Petition – Black Box Warning Levaquin for Mitochondrial Toxicity by Dr. Bennett June 2014″ backgroundcolor=”” icon=”fa-file-pdf fas” iconflip=”” iconrotate=”” iconspin=”” iconcolor=”#ff0000″ circlecolor=”” circlebordersize=”” circlebordercolor=”” outercirclebordersize=”” outercirclebordercolor=”” image=”” image_id=”” image_max_width=”” link=”https://www.dev.myquinstory.info/wp-content/uploads/2010/01/Citizen-Petition-Mitochondrial-Dr-Bennett-June-2014.pdf” linktext=”Read More” link_target=”” animation_type=”” animation_direction=”left” animation_speed=”0.3″ animation_offset=””]

Citizen Petition

Citizen Petition – Add a Black Box Warning to the Levaquin Label Regarding “Possible Mitochondrial Toxicity” by Dr. Bennett to FDA June 2014

[/fusion_content_box][fusion_content_box title=” Citizen Petition – Levaquin Label Change for by Dr. Bennett Sept 2014″ backgroundcolor=”” icon=”fa-file-pdf fas” iconflip=”” iconrotate=”” iconspin=”” iconcolor=”#ff0000″ circlecolor=”” circlebordersize=”” circlebordercolor=”” outercirclebordersize=”” outercirclebordercolor=”” image=”” image_id=”” image_max_width=”” link=”https://www.dev.myquinstory.info/wp-content/uploads/2010/01/Citizen-Petition-Psychiatric-Dr-Bennett-Sept-2014.pdf” linktext=”Read More” link_target=”” animation_type=”” animation_direction=”left” animation_speed=”0.3″ animation_offset=””]

Citizen Petition

Citizen Petition – Levaquin Label Change to Add Psychiatric Adverse Events Sept 2014

[/fusion_content_box][fusion_content_box title=”Genotoxic and cytotoxic effects of Cipro 2009″ backgroundcolor=”” icon=”fa-file-pdf fas” iconflip=”” iconrotate=”” iconspin=”” iconcolor=”#ff0000″ circlecolor=”” circlebordersize=”” circlebordercolor=”” outercirclebordersize=”” outercirclebordercolor=”” image=”” image_id=”” image_max_width=”” link=”https://www.dev.myquinstory.info/wp-content/uploads/2013/09/Cytotoxic-Effects-by-Cipro.pdf” linktext=”Read More” link_target=”” animation_type=”” animation_direction=”left” animation_speed=”0.3″ animation_offset=””]

Academic Paper

Genotoxic and cytotoxic effects of antibacterial drug, ciprofloxacin, on human lymphocytes in vitro. India 2008.

[/fusion_content_box][fusion_content_box title=”“Dear Colleague” letter written by Dr. Miriam J. de Jonge M.D. ” backgroundcolor=”” icon=”fa-file-pdf fas” iconflip=”” iconrotate=”” iconspin=”” iconcolor=”#ff0000″ circlecolor=”” circlebordersize=”” circlebordercolor=”” outercirclebordersize=”” outercirclebordercolor=”” image=”” image_id=”” image_max_width=”” link=”https://www.dev.myquinstory.info/wp-content/uploads/2010/01/Dear_Colleague_Letter_Aug_2015Fn.pdf” linktext=”Read More” link_target=”” animation_type=”” animation_direction=”left” animation_speed=”0.3″ animation_offset=””]

Dear Doctor Letter

This is a “Dear Colleague” letter written by Dr. Miriam J. de Jonge M.D. who herself was damaged by fluoroquinolones. I am posting this letter as a service to the FQ community at her request.

[/fusion_content_box][fusion_content_box title=”Dear Doctor letter written by Dr. Todd Plumb M.D.” backgroundcolor=”” icon=”fa-file-word fas” iconflip=”” iconrotate=”” iconspin=”” iconcolor=”#020ef7″ circlecolor=”” circlebordersize=”” circlebordercolor=”” outercirclebordersize=”” outercirclebordercolor=”” image=”” image_id=”” image_max_width=”” link=”https://www.dev.myquinstory.info/wp-content/uploads/2010/01/Dear-Doctor.doc” linktext=”Download Letter” link_target=”” animation_type=”” animation_direction=”left” animation_speed=”0.3″ animation_offset=””]

“Dear Doctor” Letter

This is a “Dear Doctor” letter written by Dr. Todd Plumb M.D. who himself was damaged by fluoroquinolones. This is provided as an information download to the fluoroquinolone community.

[/fusion_content_box][fusion_content_box title=”FDA Letter to Dr. Charles Bennett Dated July 10th, 2018 Detailing Psychiatric Changes to FQ Labels.” backgroundcolor=”” icon=”fa-file-pdf fas” iconflip=”” iconrotate=”” iconspin=”” iconcolor=”#ff0000″ circlecolor=”” circlebordersize=”” circlebordercolor=”” outercirclebordersize=”” outercirclebordercolor=”” image=”” image_id=”” image_max_width=”” link=”https://www.dev.myquinstory.info/wp-content/uploads/2018/07/Dr-Bennett-Levaquin-CP-Response-FDA-2014-P-1611-WM.pdf” linktext=”Read More” link_target=”” animation_type=”” animation_direction=”left” animation_speed=”0.3″ animation_offset=””]

FDA Document

Response from FDA to Dr. Charles Bennett Dated July 10th, 2018 Detailing Psychiatric Changes to FQ Labels.

[/fusion_content_box][fusion_content_box title=”FDA Internal Memo 2013 FOI Peripheral Neuropathy Mito Damage” backgroundcolor=”” icon=”fa-file-pdf fas” iconflip=”” iconrotate=”” iconspin=”” iconcolor=”#ff0000″ circlecolor=”” circlebordersize=”” circlebordercolor=”” outercirclebordersize=”” outercirclebordercolor=”” image=”” image_id=”” image_max_width=”” link=”https://www.dev.myquinstory.info/wp-content/uploads/2014/12/FDA-PN-Memo.pdf” linktext=”Read More” link_target=”” animation_type=”” animation_direction=”left” animation_speed=”0.3″ animation_offset=””]

FDA Document

Obtained by FOIA FDA Peripheral Neuropathy Internal Memo from 2013 considered by some to be a “smoking gun” in terms of the FDA acknowledging PN as being induced by mitochondrial damage.

[/fusion_content_box][fusion_content_box title=”FQ’s decreasing mtDNA encoded proteins in eukaryotic cells 2010″ backgroundcolor=”” icon=”fa-file-pdf fas” iconflip=”” iconrotate=”” iconspin=”” iconcolor=”#ff0000″ circlecolor=”” circlebordersize=”” circlebordercolor=”” outercirclebordersize=”” outercirclebordercolor=”” image=”” image_id=”” image_max_width=”” link=”https://www.dev.myquinstory.info/wp-content/uploads/2019/10/Eukaryotic_nadanaciva2010.pdf” linktext=”Read More” link_target=”” animation_type=”” animation_direction=”left” animation_speed=”0.3″ animation_offset=””]

Academic Paper

Paper that shows the fluoroquinolones have a strong effect in decreasing mtDNA-encoded proteins in eukaryotic cells 2010.

[/fusion_content_box][fusion_content_box title=”The FLOX Report Rev. 12″ backgroundcolor=”” icon=”fa-file-pdf fas” iconflip=”” iconrotate=”” iconspin=”” iconcolor=”#ff0000″ circlecolor=”” circlebordersize=”” circlebordercolor=”” outercirclebordersize=”” outercirclebordercolor=”” image=”” image_id=”” image_max_width=”” link=”https://www.dev.myquinstory.info/wp-content/uploads/2010/01/FLOX_REPORT_REV_12.pdf” linktext=”Read More” link_target=”” animation_type=”” animation_direction=”left” animation_speed=”0.3″ animation_offset=””]

Community Created Paper

The FLOX Report Rev. 12: Considered by some FQ victims as the best informational document written on FQ damage.  It is being provided here as an assistance to the fluoroquinolone victim community. Caution is advised, content can be too intense for some readers.

[/fusion_content_box][fusion_content_box title=”The FLOX Report Rev. 11″ backgroundcolor=”” icon=”fa-file-pdf fas” iconflip=”” iconrotate=”” iconspin=”” iconcolor=”#ff0000″ circlecolor=”” circlebordersize=”” circlebordercolor=”” outercirclebordersize=”” outercirclebordercolor=”” image=”” image_id=”” image_max_width=”” link=”https://www.dev.myquinstory.info/wp-content/uploads/2010/01/FLOX_REPORT_REV_11.pdf” linktext=”Read More” link_target=”” animation_type=”” animation_direction=”left” animation_speed=”0.3″ animation_offset=””]

Community Created Paper

The FLOX Report Rev. 11: Considered by some FQ victims as the best informational document written on FQ damage.  It is being provided here as an assistance to the fluoroquinolone victim community. Caution is advised, content can be too intense for some readers.

[/fusion_content_box][fusion_content_box title=”FQ use was associated with increased risk of aortic aneurysm or dissection. 2018 ” backgroundcolor=”” icon=”fa-file-pdf fas” iconflip=”” iconrotate=”” iconspin=”” iconcolor=”#ff0000″ circlecolor=”” circlebordersize=”” circlebordercolor=”” outercirclebordersize=”” outercirclebordercolor=”” image=”” image_id=”” image_max_width=”” link=”https://www.dev.myquinstory.info/wp-content/uploads/2010/01/Fluoroquinolone-use-and-risk-of-aortic-aneurysm-and-dissection-2018.pdf” linktext=”Read More” link_target=”” animation_type=”” animation_direction=”left” animation_speed=”0.3″ animation_offset=””]

Academic Paper

Fluoroquinolone use and risk of aortic aneurysm and dissection: nationwide cohort study 2018

[/fusion_content_box][fusion_content_box title=”Fluoroquinolone Utilization in the Emergency Departments of Academic Medical Centers 2003″ backgroundcolor=”” icon=”fa-file-pdf fas” iconflip=”” iconrotate=”” iconspin=”” iconcolor=”#ff0000″ circlecolor=”” circlebordersize=”” circlebordercolor=”” outercirclebordersize=”” outercirclebordercolor=”” image=”” image_id=”” image_max_width=”” link=”https://www.dev.myquinstory.info/wp-content/uploads/2010/01/Fluoroquinolone-Utilization-in-the-Emergency-Dept-of-Academic-Med-Centers.pdf” linktext=”Read More” link_target=”” animation_type=”” animation_direction=”left” animation_speed=”0.3″ animation_offset=””]

Academic Paper

Fluoroquinolone Utilization in the Emergency Departments of Academic Medical Centers. Prevalence of and risk factors for Inappropriate use. 10/28/2015

[/fusion_content_box][fusion_content_box title=”Fluoroquinolone-related neuropsychiatric and mitochondrial toxicity. Bennett 2016″ backgroundcolor=”” icon=”fa-file-pdf fas” iconflip=”” iconrotate=”” iconspin=”” iconcolor=”#ff0000″ circlecolor=”” circlebordersize=”” circlebordercolor=”” outercirclebordersize=”” outercirclebordercolor=”” image=”” image_id=”” image_max_width=”” link=”https://www.dev.myquinstory.info/wp-content/uploads/2010/01/Fluoroquinolone-related-neuropsychiatric.pdf” linktext=”Read More” link_target=”” animation_type=”” animation_direction=”left” animation_speed=”0.3″ animation_offset=””]

Academic Paper

Fluoroquinolone-related neuropsychiatric and mitochondrial toxicity: a collaborative investigation by scientists and members of a social network Published by Dr Bennett Feb 2016

[/fusion_content_box][fusion_content_box title=”Fluoroquinolone-induced serious, persistent, multisymptom adverse effects Case Study Golomb 2015″ backgroundcolor=”” icon=”fa-file-pdf fas” iconflip=”” iconrotate=”” iconspin=”” iconcolor=”#ff0000″ circlecolor=”” circlebordersize=”” circlebordercolor=”” outercirclebordersize=”” outercirclebordercolor=”” image=”” image_id=”” image_max_width=”” link=”https://www.dev.myquinstory.info/wp-content/uploads/2018/09/FQ-induced-serious-persistent-multisx-adverse-effects-BMJ-Case-Reports.pdf” linktext=”Read More” link_target=”” animation_type=”” animation_direction=”left” animation_speed=”0.3″ animation_offset=””]

Academic Paper

Case Study. Fluoroquinolone-induced serious, persistent, multisymptom adverse effects. A BMJ case study by Dr. Beartrice Golomb UCSD

[/fusion_content_box][fusion_content_box title=”Levaquin Package Insert 2009″ backgroundcolor=”” icon=”fa-file-pdf fas” iconflip=”” iconrotate=”” iconspin=”” iconcolor=”#ff0000″ circlecolor=”” circlebordersize=”” circlebordercolor=”” outercirclebordersize=”” outercirclebordercolor=”” image=”” image_id=”” image_max_width=”” link=”https://www.dev.myquinstory.info/wp-content/uploads/2010/01/Levaquin-Package-Insert.pdf” linktext=”Read More” link_target=”” animation_type=”” animation_direction=”left” animation_speed=”0.3″ animation_offset=””]

Document

Levaquin Package Insert 2009

[/fusion_content_box][fusion_content_box title=”Pediatric Levaquin Usage FDA ” backgroundcolor=”” icon=”fa-file-pdf fas” iconflip=”” iconrotate=”” iconspin=”” iconcolor=”#ff0000″ circlecolor=”” circlebordersize=”” circlebordercolor=”” outercirclebordersize=”” outercirclebordercolor=”” image=”” image_id=”” image_max_width=”” link=”https://www.dev.myquinstory.info/wp-content/uploads/2010/01/Levaquin-Pediatric-Safety-and-Use-Review-Aug-2014.pdf” linktext=”Read More” link_target=”” animation_type=”” animation_direction=”left” animation_speed=”0.3″ animation_offset=””]

FDA Document

Department of Health and Human Services Public Health Service Food and Drug Administration Center for Drug Evaluation and Research Office of Surveillance and Epidemiology Pediatric Postmarketing Pharmacovigilance and Drug Utilization Review 04/27/2012

[/fusion_content_box][fusion_content_box title=”Metal Complexes of Quinolone Antibiotics 2003″ backgroundcolor=”” icon=”fa-file-pdf fas” iconflip=”” iconrotate=”” iconspin=”” iconcolor=”#ff0000″ circlecolor=”” circlebordersize=”” circlebordercolor=”” outercirclebordersize=”” outercirclebordercolor=”” image=”” image_id=”” image_max_width=”” link=”https://www.dev.myquinstory.info/wp-content/uploads/2010/01/Metal-Complexes-of-Quinolones-and-their-applications.pdf” linktext=”Read More” link_target=”” animation_type=”” animation_direction=”left” animation_speed=”0.3″ animation_offset=””]

Academic Paper

Metal Complexes of Quinolone Antibiotics and Their Applications: An Update Valentina Uivarosi 2013

[/fusion_content_box][fusion_content_box title=”Musculoskeletal Complications of Fluoroquinolones Mayo 2011″ backgroundcolor=”” icon=”fa-file-pdf fas” iconflip=”” iconrotate=”” iconspin=”” iconcolor=”#ff0000″ circlecolor=”” circlebordersize=”” circlebordercolor=”” outercirclebordersize=”” outercirclebordercolor=”” image=”” image_id=”” image_max_width=”” link=”https://www.dev.myquinstory.info/wp-content/uploads/2012/03/Hall-Finnoff-Smith-2011.pdf” linktext=”Read More” link_target=”” animation_type=”” animation_direction=”left” animation_speed=”0.3″ animation_offset=””]

Clinical Review

Musculoskeletal Complications of Fluoroquinolones: Guidelines and Precautions for Usage in the Athletic Population Mederic M. Hall, MD, Jonathan T. Finnoff, DO, Jay Smith, MD Mayo 2011

[/fusion_content_box][fusion_content_box title=”Peripheral Neuropathy Associated with Fluoroquinolones Cohen 2001″ backgroundcolor=”” icon=”fa-file-pdf fas” iconflip=”” iconrotate=”” iconspin=”” iconcolor=”#ff0000″ circlecolor=”” circlebordersize=”” circlebordercolor=”” outercirclebordersize=”” outercirclebordercolor=”” image=”” image_id=”” image_max_width=”” link=”https://www.dev.myquinstory.info/wp-content/uploads/2010/10/Neuropathy.pdf” linktext=”Read More” link_target=”” animation_type=”” animation_direction=”left” animation_speed=”0.3″ animation_offset=””]

Academic Paper

The Article “Peripheral Neuropathy Associated with Fluoroquinolones” written by Jay S Cohen M.D. and published in the Annals of Pharmacotherapy in December 2001.

[/fusion_content_box][fusion_content_box title=”Non-antibiotic effects of fluoroquinolones in mammalian cells 2015 Mayo” backgroundcolor=”” icon=”fa-file-pdf fas” iconflip=”” iconrotate=”” iconspin=”” iconcolor=”#ff0000″ circlecolor=”” circlebordersize=”” circlebordercolor=”” outercirclebordersize=”” outercirclebordercolor=”” image=”” image_id=”” image_max_width=”” link=”https://www.dev.myquinstory.info/wp-content/uploads/2010/01/Non-antibiotic-effects-of-fluoroquinolones-in-mammalian-cells.pdf” linktext=”Read More” link_target=”” animation_type=”” animation_direction=”left” animation_speed=”0.3″ animation_offset=””]

Academic Paper

Non-antibiotic effects of fluoroquinolones in mammalian cells. This important July 2015 Mayo paper documents that “FQ antibiotics induce global epigenetic changes”

[/fusion_content_box][fusion_content_box title=”Nonclassical Biological Activities of Quinolone Derivatives Nov. 2011″ backgroundcolor=”” icon=”fa-file-pdf fas” iconflip=”” iconrotate=”” iconspin=”” iconcolor=”#ff0000″ circlecolor=”” circlebordersize=”” circlebordercolor=”” outercirclebordersize=”” outercirclebordercolor=”” image=”” image_id=”” image_max_width=”” link=”https://www.dev.myquinstory.info/wp-content/uploads/2010/01/Nonclassical-Biological-Activities-of-Quins.pdf” linktext=”Read More” link_target=”” animation_type=”” animation_direction=”left” animation_speed=”0.3″ animation_offset=””]

Academic Paper

Nonclassical Biological Activities of Quinolone Derivatives 2012

[/fusion_content_box][fusion_content_box title=”Citizen Petition Black Box Warning FQAD June 2019″ backgroundcolor=”” icon=”fa-file-pdf fas” iconflip=”” iconrotate=”” iconspin=”” iconcolor=”#ff0000″ circlecolor=”” circlebordersize=”” circlebordercolor=”” outercirclebordersize=”” outercirclebordercolor=”” image=”” image_id=”” image_max_width=”” link=”https://www.dev.myquinstory.info/wp-content/uploads/2019/06/SONAR-Citizens-Petition-re-Levaquin-Label-June-20-2019-002.pdf” linktext=”Read More” link_target=”” animation_type=”” animation_direction=”left” animation_speed=”0.3″ animation_offset=””]

Citizen Petition

Dr Bennett & Sonar Citizen Petition Black Box Warning FQAD June 2019

[/fusion_content_box][fusion_content_box title=” Not Your Mothers Mito Not Your Mother’s Mitochondrial Disease – Myths and Facts About Mitochondrial Cytopathies” backgroundcolor=”” icon=”fa-file-pdf fas” iconflip=”” iconrotate=”” iconspin=”” iconcolor=”#ff0000″ circlecolor=”” circlebordersize=”” circlebordercolor=”” outercirclebordersize=”” outercirclebordercolor=”” image=”” image_id=”” image_max_width=”” link=”https://www.dev.myquinstory.info/wp-content/uploads/2010/01/Not-Your-Mothers-Mito.pdf” linktext=”Read More” link_target=”” animation_type=”” animation_direction=”left” animation_speed=”0.3″ animation_offset=””]

Article

Not Your Mother’s Mitochondrial Disease: Myths & Facts About Mitochondrial Cytopathies By Sumit Parikh, M.D. & Bruce H. Cohen, M.D.  Cleveland Clinic 2006

[/fusion_content_box][fusion_content_box title=”Possible involvement of DEC1 on the adverse effects of quinolone antibiotics. 2010″ backgroundcolor=”” icon=”fa-file-pdf fas” iconflip=”” iconrotate=”” iconspin=”” iconcolor=”#ff0000″ circlecolor=”” circlebordersize=”” circlebordercolor=”” outercirclebordersize=”” outercirclebordercolor=”” image=”” image_id=”” image_max_width=”” link=”https://www.dev.myquinstory.info/wp-content/uploads/2010/01/Shi-2010-DEC1.pdf” linktext=”Read More” link_target=”” animation_type=”” animation_direction=”left” animation_speed=”0.3″ animation_offset=””]

Academic Paper

Possible involvement of DEC1 on the adverse effects of quinolone antibiotics. China 2010

[/fusion_content_box][fusion_content_box title=”Quinolone binding to DNA is mediated by magnesium ions. 1992″ backgroundcolor=”” icon=”fa-file-pdf fas” iconflip=”” iconrotate=”” iconspin=”” iconcolor=”#ff0000″ circlecolor=”” circlebordersize=”” circlebordercolor=”” outercirclebordersize=”” outercirclebordercolor=”” image=”” image_id=”” image_max_width=”” link=”https://www.dev.myquinstory.info/wp-content/uploads/2010/01/Magnesium-IO-Binding-to-DNA.pdf” linktext=”Read More” link_target=”” animation_type=”” animation_direction=”left” animation_speed=”0.3″ animation_offset=””]

Academic Paper

Quinolone binding to DNA is mediated by magnesium ions. Italy June 12, 1992

[/fusion_content_box][fusion_content_box title=”Antibiotics Currently in Clinical Development as of May 2016″ backgroundcolor=”” icon=”fa-file-pdf fas” iconflip=”” iconrotate=”” iconspin=”” iconcolor=”#ff0000″ circlecolor=”” circlebordersize=”” circlebordercolor=”” outercirclebordersize=”” outercirclebordercolor=”” image=”” image_id=”” image_max_width=”” link=”https://www.dev.myquinstory.info/wp-content/uploads/2010/01/Antibiotics-Currently-in-Clinical-Development.pdf” linktext=”Read More” link_target=”” animation_type=”” animation_direction=”left” animation_speed=”0.3″ animation_offset=””]

Document

Antibiotics Currently in Clinical Development As of March 2016,

[/fusion_content_box][fusion_content_box title=”Comprehensive Quinolone List” backgroundcolor=”” icon=”fa-file-pdf fas” iconflip=”” iconrotate=”” iconspin=”” iconcolor=”#ff0000″ circlecolor=”” circlebordersize=”” circlebordercolor=”” outercirclebordersize=”” outercirclebordercolor=”” image=”” image_id=”” image_max_width=”” link=”https://www.dev.myquinstory.info/wp-content/uploads/2014/05/quinolone_list.pdf” linktext=”Read More” link_target=”” animation_type=”” animation_direction=”left” animation_speed=”0.3″ animation_offset=””]

Document

Comprehensive Quinolone List Courtesy of My Quin Story: Life After Levaquin

[/fusion_content_box][fusion_content_box title=”Repairing Damaged Plasma Membrane 2017″ backgroundcolor=”” icon=”fa-file-pdf fas” iconflip=”” iconrotate=”” iconspin=”” iconcolor=”#ff0000″ circlecolor=”” circlebordersize=”” circlebordercolor=”” outercirclebordersize=”” outercirclebordercolor=”” image=”” image_id=”” image_max_width=”” link=”https://www.dev.myquinstory.info/wp-content/uploads/2010/01/Membrane-Repair.pdf” linktext=”Read More” link_target=”” animation_type=”” animation_direction=”left” animation_speed=”0.3″ animation_offset=””]

Document

Reparing the Damaged Plasma Membrane of the Cell and Membrane Bound Organelles 2014

[/fusion_content_box][fusion_content_box title=”High Incidence of New-Onset Joint Pain in Patients on Fluoroquinolones as Antituberculous Treatment” backgroundcolor=”” icon=”fa-file-pdf fas” iconflip=”” iconrotate=”” iconspin=”” iconcolor=”#ff0000″ circlecolor=”” circlebordersize=”” circlebordercolor=”” outercirclebordersize=”” outercirclebordercolor=”” image=”” image_id=”” image_max_width=”” link=”https://www.dev.myquinstory.info/wp-content/uploads/2020/01/New-Onset-Joint-Pain-011420.pdf” linktext=”Read More” link_target=”” animation_type=”” animation_direction=”left” animation_speed=”0.3″ animation_offset=””]

Academic Paper

Fluoroquinolone-associated joint pain  in patients with tuberculosis.  This paper shows delayed onset of FQ pathology. 

[/fusion_content_box][fusion_content_box title=”Risk of gastrointestinal perforation in patients taking oral therapy: An analysis of nationally representative cohort” backgroundcolor=”” icon=”fa-file-pdf fas” iconflip=”” iconrotate=”” iconspin=”” iconcolor=”#ff0000″ circlecolor=”” circlebordersize=”” circlebordercolor=”” outercirclebordersize=”” outercirclebordercolor=”” image=”” image_id=”” image_max_width=”” link=”https://www.dev.myquinstory.info/wp-content/uploads/2020/01/Gastro-Perforation-with-FQs-plone-2017.pdf” linktext=”Read More” link_target=”” animation_type=”” animation_direction=”left” animation_speed=”0.3″ animation_offset=””]

Academic Paper

Risk of gastrointestinal perforation in patients taking oral fluoroquinolone therapy: An analysis of nationally representative cohort.  China 2017.

[/fusion_content_box][fusion_content_box title=”Fluoroquinolones Potent Form of Chemotherapy” backgroundcolor=”” icon=”fa-file-pdf fas” iconflip=”” iconrotate=”” iconspin=”” iconcolor=”#ff0000″ circlecolor=”” circlebordersize=”” circlebordercolor=”” outercirclebordersize=”” outercirclebordercolor=”” image=”” image_id=”” image_max_width=”” link=”https://www.dev.myquinstory.info/wp-content/uploads/2020/07/CEO-FQs-Potent-Form-Chemo-050620.pdf” linktext=”Read More” link_target=”” animation_type=”” animation_direction=”left” animation_speed=”0.3″ animation_offset=””]

Academic Paper

The purpose of this viewpoint is to describe the unfortunate consequences that  can occur in a portion of patients taking systemic fluoroquinolones, and to share the view that eye-care practitioners should consider them cytotoxic and potential anti-cancer treatments. Australia May, 2020

[/fusion_content_box][fusion_content_box title=”Off-label use of oral fluoroquinolone antibiotics in outpatient settings 2006 to 2012.” backgroundcolor=”” icon=”fa-file-pdf fas” iconflip=”” iconrotate=”” iconspin=”” iconcolor=”#ff0000″ circlecolor=”” circlebordersize=”” circlebordercolor=”” outercirclebordersize=”” outercirclebordercolor=”” image=”” image_id=”” image_max_width=”” link=”https://www.dev.myquinstory.info/wp-content/uploads/2020/10/Off-Label-Use-of-FQs-almalki2016.pdf” linktext=”Read More” link_target=”” animation_type=”” animation_direction=”left” animation_speed=”0.3″ animation_offset=””]

Academic Paper

The aim of this study was to evaluate the practice pattern of off-label use of fluoroquinolones (FQs) in ambulatory settings and to identify the related risk factors. United States, 2016

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Do you know an important fluoroquinolone related document that belongs here? Send me the link or Contact me and let me know.  Thanks.

Denotes papers that I co-authored, assisted in publication, or provided fluoroquinolone related data to the author.

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